NUTRITIONAL
GENOMICS

Until recently, the etiology of chronic diseases had been described in terms of biochemical and

physiological changes in tissue function. Unfortunately, by the time changes are diagnosed, meta-
bolic dysfunctions already exist, and therapy is designed primarily to reduce the progression of the

disease state. Selective dietary regimens and pharmacologic agents have been used to block or slow
the progression and alleviate some of the side effects of these diseases. Population groups having

similar chronic disease characteristics have consistently been noted to contain responders, nonre-
sponders, and negative responders to each therapeutic regimen.