Magnesium in Human Health
and Disease

Magnesium is an essential mineral which is required for growth and survival of humans. Since magnesium
is a mineral and not synthesizable, it must be obtained through dietary foods and/or supplements.
Magnesium is found in many sources, primarily whole grains, green leafy vegetables, nuts, and

legumes. Even with many dietary sources, only about one-third of Americans maintain the appropri-
ate dietary intake of magnesium. A very small number of people have drug-induced severe magne-
sium de fi ciency. So major issues reviewed are the bene fi ts of magnesium supplementation to reach

(a) recommended intakes or (b) above -recommended intakes to promote health or treat various
diseases and risk factors.